C-Reactive Protein (CRP) is the best-known among the acute-phase proteins. CRP concentration increase in response to inflammation, postoperative conditions or tissue damage. CRP normally present in low concentration (< 5 mg/L) can raise rapidly during the acute inflammatory process with values up to 500 mg/L during bacterial infections. In recent years, studies have shown that in apparently healthy individuals a direct correlation between the level of CRP and the risk of developing coronary heart disease (CHD) exists.
CRP has also been reported as a potential marker for monitoring Statin therapy. The various clinical applications of CRP require access to both a sensitive and a wide range assay.
CRP Vario was designed to fulfill both requirements.