History of Sentinel Diagnostics

HISTORY

Sentinel Diagnostics was founded in Milan in 1983.

Sentinel Diagnostics uses the experience gained in the development and production of diagnostic kits for Clinical Chemistry, Immunology and Molecular Diagnostic.

Today the Sentinel Diagnostics® brand is well known and appreciated on a worldwide scale, thanks to the increasingly fruitful partnerships with prestigious companies in the diagnostics sector, that have chosen Sentinel Diagnostics as the ideal partner for the realization of diagnostic kits dedicated for use on their automated analyzers.

Listed below are some of the most significant products developed by Sentinel

1983
Foundation

1983<br><strong>Foundation</strong>

Sentinel Diagnostics was founded in Milan in 1983

1984
Iron

1984<br> <strong>Iron</strong>

Direct method – Chromogen FERENE S

1988
Total & Direct Bilirubin

1988<br> <strong>Total & Direct Bilirubin</strong>

Colorimetric Method – Bilirubin Oxidase

1989
Inorganic Phosphorus

1989<br><strong>Inorganic Phosphorus</strong>

Enzymatic Colorimetric Method

1990
Copper

1990<br><strong>Copper</strong>

Direct method – Chromogen DiBr-PAESA

1992
Zinc

1992<br><strong>Zinc</strong>

Direct method – Chromogen 5Br-PAPS

1995
Magnesium

1995<br><strong>Magnesium</strong>

Enzymatic UV method

1996
Lipase

1996<br><strong>Lipase</strong>

Direct method – Substrate Methylresorufin – derivative – 1996 – 510(k) FDA: K961179

1998
Cholinesterase

1998<br><strong>Cholinesterase</strong>

Optimized DGKC method – 1998 – 510(k) FDA: K981800

2001
Lithium

2001<br><strong>Lithium</strong>

Direct Colorimetric Method with porphyrin complex

2002
CRP Ultra

2002<br> <strong>CRP Ultra</strong>

High sensitive latex Turbidimetric method

2003
ALT Microwell

2003<br><strong>ALT Microwell</strong>

IFCC Optimized Enzymatic Colorimetric method on microplate

2004
Ammonia

2004<br><strong>Ammonia</strong>

Direct Enzymatic Method

2004
FOB Gold®

2004<br><strong>FOB Gold<sup>®</sup></strong>

First quantitative Immunological test for the determination of human hemoglobin in feces in complete automation using a patented collection system, which can be adapted for use on most automated analyzers

2005
HbA1c

2005<br><strong>HbA1c</strong>

One-step Latex Direct Method

2006
Creatinine Enzymatic

2006<br><strong>Creatinine Enzymatic</strong>

Enzymatic Colorimetric Method – sarcosine oxidase

2007
CRP Vario

2007<br><strong>CRP Vario</strong>

High sensitive latex Turbidimetric method with wide measuring range

2008
CK-MB

2008<br><strong>CK-MB</strong>

IFCC Optimized Immunological Kinetic Method

2008
Homocysteine

2008<br><strong>Homocysteine</strong>

Enzymatic Colorimetric Method –  bi-reagent

2009
Cystatin C

2009<br><strong>Cystatin C</strong>

Latex Immunoturbidimetric method

2010
FOB Gold® Tube NG

2010<br><strong>FOB Gold<sup>®</sup> Tube NG</strong>

New Generation fecal collection device to be used as a primary tube on automated analyzers

2010
Syphilis TP

2010<br><strong>Syphilis TP</strong>

Latex immunoturbidimetric method

2011
STAT-NAT®

2011<br><strong>STAT-NAT<sup>®</sup></strong>

Innovative stabilization technology for simple and standardized molecular diagnostics

2011
FOB Gold® NG

2011<br><strong>FOB Gold<sup>®</sup> NG</strong>

New generation of the latex turbidimetric quantitative determination of human haemoglobin in feces

2011
STAT-NAT® DNA-Mix

2011<br><strong>STAT-NAT<sup>®</sup> DNA-Mix</strong>

Universal and complete lyophilized master mix for gene amplification

2012
STAT-NAT® Malaria Screening

2012<br><strong>STAT-NAT<sup>®</sup> Malaria Screening</strong>

Multiplex PCR test for Malaria screening

2012
STAT-NAT® Malaria Typing

2012<br><strong>STAT-NAT<sup>®</sup> Malaria Typing</strong>

Multiplex PCR test for Malaria typing

2013
STAT-NAT® RNA-Mix

2013<br><strong>STAT-NAT<sup>®</sup> RNA-Mix</strong>

Universal and complete lyophilized one-step master mix for retrotranscription and nucleic acid amplification

2013
STAT-NAT® Leishmania Mix

2013<br><strong>STAT-NAT<sup>®</sup> Leishmania Mix</strong>

Kit in PCR Real-Time per una diagnosi accurata e semplice della Leishmaniosi

2014
UIBC Liquid

2014<br><strong>UIBC Liquid</strong>

Two liquid reagents for the measurement of UIBC (unsaturated iron-binding capacity) in serum

2015
ACE Liquid

2015<br><strong>ACE Liquid</strong>

Enzymatic method for the determination of angiotensin converting enzyme activity (ACE) in serum or plasma

2017
Lipase NG

2017<br><strong>Lipase NG</strong>

New generation ready-to-use test for lipase measurement in serum or plasma

2018
CALiaGOLD®

2018<br><strong>CALiaGOLD<sup>®</sup></strong>

Quantitative latex immunoassay for fecal calprotectin measurement

2019
STAT-NAT® Adenovirus

2019</br><strong>STAT-NAT<sup>®</sup> Adenovirus</strong>

Lyophilized RT qPCR mix for the detection and quantification of Adenovirus in human samples

2019
STAT-NAT® BKV

2019</br><strong>STAT-NAT<sup>®</sup> BKV</strong>

Lyophilized RT qPCR mix for the detection and quantification of polyomavirus BK (BKV) in human samples

2019
STAT-NAT® EBV

2019</br><strong>STAT-NAT<sup>®</sup> EBV</strong>

Lyophilized RT qPCR mix for the detection and quantification of Epstein Barr Virus (EBV) in human samples

2019
STAT-NAT® HHV-6

2019</br><strong>STAT-NAT<sup>®</sup> HHV-6</strong>

Lyophilized RT qPCR mix for the detection and quantification of Human herpesvirus 6 (HHV-6) in human samples

2019
STAT-NAT® HSV1 and HSV-2

2019</br><strong>STAT-NAT<sup>®</sup> HSV1 and HSV-2</strong>

Lyophilized RT qPCR mix for the detection and quantification of Herpes Symplex Virus Type 1 (HSV-1) and Type 2 (HSV-2) in human samples

2019
STAT-NAT® VRE

2019</br><strong>STAT-NAT<sup>®</sup> VRE</strong>

Lyophilized qualitative RT PCR mix for the detection of Vancomycin-Resistant Enterococcus (VRE) in samples extracted by cell culture

2020
STAT-NAT® COVID-19

2020<br><strong>STAT-NAT<sup>®</sup> COVID-19</strong>

Lyophilized Real-Time PCR mix for the detection of novel Coronavirus disease (COVID-19)

2021
COVID-19 Serological Assays

2021 <br><strong>COVID-19 Serological Assays</strong>

Serological tests for quantitative and qualitative detection of total antibodies against Spike RBD S1 protein or Nucleocapsid (NC) protein of SARS-CoV-2

2022
New analyzers: SENTiFIT®800 e SENTiNAT®200

2022 <br><strong> New analyzers: SENTiFIT<sup>®</sup>800 e SENTiNAT<sup>®</sup>200</strong>

Fully automated analyzers. For high volume of fecal testing and multiparameter analyses for pathogen detection.

2023
Acquisition of Eureka Lab Division

2023<br><strong> Acquisition of Eureka Lab Division</strong>

Sentinel Diagnostics (Sentinel CH. SpA) extends its expertise and activities in the field of chromatography and mass spectrometry through the acquisition of EUREKA s.r.l.- LAB DIVISION