PLATELET AGGREGATION PROFILER PAP-8E
The PAP-8E from Bio/Data Corporation is the world’s most advanced aggregometer for laboratory applications. Exceptional ease of use and standardized test procedures allow for rapid and routine testing of platelet function.
The PAP-8E is designed to support diagnoses of hemostasis disorders including von Willebrand Disease (vWD), Glanzmann’s disease, HIT, Bernard Soulier Syndrome, and Sticky Platelet Syndrome as well as to precisely monitor the use of anti-platelet drugs during clinical trials or patient therapy. (Aspirin, ReoPro®, Aggrenox®, Asasantin®, Pletal®, Plavix®, Persantine®, Integrelin®, Effient®, Ticlid).
The Platelet Aggregation Profiler, PAP-8E, is intended for usein clinical, research, university, biotechnology and pharmaceutical laboratories. The system measures the rate and extent of aggregation, agglutination, activation and inhibition reactions. Comprehensive results include area under the curve and area under the slope.
Clinical Laboratory
- Measure Ristocetin CoFactor
- Confirm diagnosis of HIT (Heparin Induced Thrombocytopenia)
- Evaluate and monitor patients with platelet funcion abnormalities
- Manage Anti-Platelet therapy
- Pre and post-operative support of LVAD patients
(Left Ventricular Assist Devices).
Pharmaceutical Laboratory
- Study Anti-Platelet compounds
- examine anti-infiammatory or other compounds
- Leukocyte aggregation and platelet-leukocyte interaction
- Microvolume capacity for discovery
- Pre-clinical or small animal model studies.
BioTechnology Laboratory
- Measue activity and effectiveness of ricombination agents
- Study effects of engineered surfaces on platelet function
- Investigate dietary influences on platelet function.
Research laboratory
- Evaluate platelet-vascular interactions
- Examin anti-platelet and lytic agent effect in thrombotic models or events.
Veterinary Laboratory
- Measure Ristocetin CoFactor activity in canine
and porcine species - Study platelet function abnormalities in animals
- Measure platelet function
in animal models.
- 8 Test Channel Aggregometer
- Electronic Pipette
- Computer with Monitor
- Software
- Printer
- Walk-Away Operation
- User-defined Test Templates and Protocols
- Minimal Patient Sample (225μL) Required
- Touch Screen Operation
- On Screen Directions and Procedures
Product specifications
| Test wells | eight (stirred) |
| Activation wells | eight (stirred) |
| Incubation wells | eight (not stirred) |
| Reagent wells | two (37° C with stirring – adapters provided to accomodate varous size vials) |
| Temperature control | test and incubation blocks heated to 37° C +/- 0.5 °C |
| Digital stir speed control | 0 – 1200 rpm (present for standard tests – selectable for user defined tests) |
| Test volume | 250 uL o 500 uL |
| Sample volume | 225 uL o 450 uL |
| Reagent volume | 25 uL o 50 uL |
| Sensitivity | 50,000 platelet/mm3 |
| Light source | LED (Light Emitting Diodes) |
| Wavelength | UV 400 – 430 nm |
| Trace filter | definibile dall’ operatore |
Software
- Touch Screen inteface
- All Windows-R features available
- Reagents an patients identification entry bar code scanner
- 3 or 4 point standard curves for Ristocetin CoFactor assay
- CoFactor assay
- Eight digital timers, countdown, elapsed time, audible alarm
- On screen keyboard
- Data export to Prism 5, spreadsheet, templatem presentation software and LIS (Laboratory Information System)
- Two level security and operator tracking
- Data analysis: User selectable point and functions, Primary and secondary Slope, Area under the curve, Area under the Slope, Lag phase, Shape change, Disaggregation
- Data sorting and Archiving
- Pre-loaded test parametrers
- User defined test protocols
- On screen help
- Online operator manual
- Diagnostics: Start-up, automatic and user selected
Accessories
Programmable pipettor
- Electronic with memory
- 10 to 300 uL capacity
- Multi-dispensing function
- Preprogrammed volumes
GraphPad-R Software Prism 5
- Bio-analytical software
- Templates for clinical, research, pharmaceutical, biotechnology laboratories and contract research organizations.
Bar Code Scanner (optional)
- Bi-directional
- Supports 123 Scan setup utility
- RSS (Reduced Space Symbology)
- R GTIN-Compliant
- Decode capability (16 Standard codes)
PC specifications
- Dell Optiplex-TM
- Processor Pentium-R 3.2 GHz
- RAM 512 MB
- Hard disk 40 GB
- DVD/CD Read/Write 24X drive
- USB 2.0 (2) and RS232 (1) ports
- Network Ethernet
- Monitor ELO 1525L, Touch Screen, 15 inch, Flat LCD panel, Active Matrix, Angolo 170°, 5-wire resistive
- Stendard keyboard, Touch Screen keyboard, Mouse
- Multifunction printer, color, inkjet
- Windows-R XP Professional Multi-Language Pack
Dimensions
- Typical configuration made of PAP-8E , PC e Monitor
- Height: 57,2 cm
- Width: 35,6 cm
- Length: 55,1 cm
- Weight: 21,0 Kg
Limited warranty
Two years parts and labor at the authorized distributor
Safety certifications
The PAP-8E analyser module meets: European Union directive 98/79/EC invitro diagnostic medical devices, European Union electromagnetic compatibility directive 89/336/EEC, European Union low voltage directive 73/23/EEC, European standards: EN 61010-1:2001, Safety requirements for measurament control and laboratory use EN61010-2101:2002, Particular requirements for invitro diagnostic (IVD) medical equipment, EMC standards – EN 61326, EN 61000-3-2; EN 61000-3-3.
The PAP-8E analyser is designed to agree with the following standards: UL 61010-1 Safety requirements for electrical equipment for measurement, control and laboratory use – Part1: general requirements.
All accessory components have individual UL and CE certification.
Notes
The specifications for the PAP-8E and accessories are subject to change without notice.
– OptiPlex-TM ia a trademark of Dell Corporation
– Pentium-R is a registered trademark of Intel Corporation
– Platelet Aggregation Profiler -R is a registered trademark of Bio/Data Corporation
– Prism-R is a registered trademark of GraphPad, Inc.
– Reduced Space Symbology-R (RSS) is a registered trademark of Symbol Technologies, Inc.
– Windows-R is a registered trademark of Microsoft Corporation